Pyridazine Derivatives (pyridazine + derivative)

Distribution by Scientific Domains


Selected Abstracts


Pyridazine Derivatives and Related Compounds.

CHEMINFORM, Issue 19 2006
Part 21.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


New Cycloaddition of Diarylazines with 1,2-Dehydrobenzene, 1,1,2,2-Tetracyanoethylene, and Dibenzoylacetylene , Facile Synthesis of Acridinones (III), Pyrazolidine (V), and Pyridazine Derivatives (VII).

CHEMINFORM, Issue 35 2005
Ashraf A. Aly
No abstract is available for this article. [source]


Preparation of ,,,-Unsaturated ,-Keto Aldehydes and New Tetronic Acid and Pyridazine Derivatives by Oxidative Transformations of Alkoxyallene-Based Dihydrofurans.

CHEMINFORM, Issue 43 2004
Oliver Floegel
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


Heterocyclic Synthesis with Ethyl ,-(3-Carbamoyl-4,5,6,7-tetrahydrobenzo [b]thiophen-2-ylhydrazono)acetates: An Expeditious Synthetic Approach to Polyfunctionally Substituted Pyran, Pyridine, and Pyridazine Derivatives.

CHEMINFORM, Issue 40 2004
Rafat M. Mohareb
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


ChemInform Abstract: Bicyclic [b]-Heteroannulated Pyridazine Derivatives.

CHEMINFORM, Issue 52 2001
Part 9.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: A Convenient Route to New Pyrrolo[1,2-c]pyrimidone, Thiazolo[3,4-c]pyrimidone and Pyrimido[4,5-d]pyridazine Derivatives.

CHEMINFORM, Issue 33 2009
Nabila A. Kheder
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


Synthesis and Biological Evaluation of 6-Aryl-6H-pyrrolo[3,4-d]pyridazine Derivatives as High-Affinity Ligands of the ,2, Subunit of Voltage-Gated Calcium Channels.

CHEMINFORM, Issue 35 2004
Tao Hu
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


New 1,2,3-Triazolo[4,5-d]1,2,4-triazolo[3,4-b]pyridazine Derivatives.

CHEMINFORM, Issue 5 2003
Part 2.
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


ChemInform Abstract: Design, Synthesis, and Structure,Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase Inhibitors.

CHEMINFORM, Issue 49 2001
Jean-Marie Contreras
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


Heterocyclic synthesis with ethyl ,-(3-carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylhydrazono)acetates: An expeditious synthetic approach to polyfunctionally substituted pyran, pyridine, and pyridazine derivatives

HETEROATOM CHEMISTRY, Issue 4 2004
Rafat M. Mohareb
Ethyl ,-(3-carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylhydrazono)acetates 1 were prepared and established as previously described by our research group. Their reactivity toward a variety of active methylene reagents was studied to give pyran, pyridine, and pyridazine derivatives. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:300,306, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20019 [source]


Diverse reactivity of ,-carbanions derived from alkylidenephosphoranes toward 2-(1,5 -diazynylidene)-1H -indene-1,3-(2H)dione.

JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 6 2008
General approach to conjugated oxadiazines, pyridazines, spiro[3]pyrazoles
Different types of phosphonium carbanions were applied to 2-diazonio-1,3-dioxo-2,3-dihydro-1H -inden-2-ide (1) in order to synthesize a number of condensed and fused N -heterocycles. When 1 was treated with cyanomethyltriphenylphosphonium chloride oxadiazine-, and pyridazine derivatives were obtained whereas bis-indanylidene derivatives resulted from the reaction of 1 with methyl_ and ethyltriphenylphosphonium bromides. On the other hand, a series of substituted and unsubstituted spiro[3,]pyrazoles were obtained from the di azo substrate when reacted with vinyl_and allyltriphenylphosphonium bromides. [source]


Synthesis of novel pyrazolo[3,4- d]pyridazine, pyrido[1,2- a]benzimidazole, pyrimido[1,2- a]benzimidazole and triazolo[4,3- a]pyrimidine derivatives

JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 6 2008
Mohamed R. Shaaban
4-Acetyl-5-methyl-1-phenyl-1H -pyrazole reacts with dimethylformamide dimethylacetal (DMF-DMA) to afford the corresponding (E)1-(5-methyl-1-phenyl-1H -pyrazol-4-yl)-3-(N,N -dimethylamino)-2-propen-1-one. The latter product undergoes regioselective 1,3-dipolar cycloaddition with nitrilimines and nitrile oxides to afford the novel 3-aroyl-4-(5-methyl-1-phenyl-1H -pyrazol-4-yl)carbonyl-1-phenylpyrazole and 3-aroyl-4-(5-methyl-1-phenyl-1H -pyrazol-4-yl)carbonyl isoxazole derivatives, respectively. It reacts also with 1H -benzimidazole-2-acetonitrile, 2-aminobenzimidazole and 3-amino-1,2,4-triazole to afford the novel pyrido[1,2- a]benzimidazole, pyrimido[1,2- a]benzimidazole and the triazolo[4,3- a]pyrimidine derivatives, respectively. The reaction of 3-aroyl-4-(5-methyl-1-phenyl-1H -pyrazol-4-yl) carbonyl-1-phenylpyrazole derivatives with hydrazine hydrate led to a new pyrazolo[3,4- d]pyridazine derivatives. [source]


Regioselective synthesis of some novel pyrazoles, isoxazoles, pyrazolo[3,4- d]pyridazines and isoxazolo[3,4- d]pyridazines pendant to benzimidazole

JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 1 2007
Mohamed R. Shaaban
2-Acetyl-1-methyl-1H -benzimidazole reacts with dimethylformamide-dimethyl-acetal (DMF-DMA) to afford the corresponding E -1-(1-methyl-1H -benzimidazol-2-yl)-3- N,N -dimethylaminoprop-2-enone. The latter compound reacts regioselectively with some nitrilimines and nitrile oxides to afford the corresponding pyrazole and isoxazole derivatives, respectively. These reaction products react with hydrazine hydrate to give the novel pyrazolo[3,4- d]pyridazine and isoxazolo[3,4- d]pyridazine derivatives, respectively. [source]


Synthesis of pyridazine derivatives through the unexpected intermediate 5-amino- 4-cyano -2,3-dihydro-furan-2,3-disulfonic acid disodium salt

JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 6 2003
Barbara Cacciari
An unexpected compound (5-amino-4-cyano-2,3-dihydrofuran-2,3-disulfonic acid disodium salt, 4) was isolated from the reaction of glyoxale bis hydrogen sulfite disodium salt with malononitrile. Its structure was undoubtly identified through crystal structure analysis. Compound 4 was highly stable and it was isolated easily and in a very high yield. Its reactivity was studied in the reactions with some hydrazine derivatives in order to obtain different pyridazine analogs. [source]