Literature Support (literature + support)

Distribution by Scientific Domains


Selected Abstracts


Negative pressure wound therapy: treating a venomous insect bite

INTERNATIONAL WOUND JOURNAL, Issue 1 2007
Michael S Miller
Abstract Reports of spider bites appear throughout North America. Bites associated with the brown recluse spider (Loxosceles recluse) cause serious medical complications because the venom of this spider contains a powerful necrotising agent with the potential to cause severe cutaneous necrosis. Although not much is known regarding the application of negative pressure wound therapy (NPWT) to spider bites, this therapy has considerable literature support for its efficacy, cost-effectiveness and ease of use in chronic, difficult-to-heal wounds. A case study using NPWT to successfully treat a non healing upper arm wound presumed due to a venomous spider bite is presented here. The patient was successfully treated with a new, less costly NPWT product called the Versatile 1® and a new combination drain plus dressing called the Miller DermiVex® drain, both manufactured by Blue Sky Medical (Carlsbad, CA). [source]


Study on the antinociceptive action of Tyr-K-MIF-1, a peptide from the MIF family

AUTONOMIC & AUTACOID PHARMACOLOGY, Issue 2 2007
R. Zamfirova
Summary 1 Tyr-K-MIF-1 is a melanocyte inhibiting factor (MIF) neuropeptide, isolated from the brain. Opposite to other MIFs (Tyr-MIF-1, Tyr-W-MIF-1), it has a very low affinity for opiate , -receptors, but interacts with Tyr-MIF-1 specific binding sites. Tyr-MIF-1 and Tyr-W-MIF-1 evoke antinociception mainly by activating opioid receptors. We investigated the possible antinociceptive effect of Tyr-K-MIF-1 and the involvement of histaminergic system in its mechanism of action. 2 Tested on rats by paw-pressure test, Tyr-K-MIF-1 (0.5, 1 and 2 mg kg,1) was associated with short-lasting analgesia, which was abolished by naloxone (1 mg kg,1). 3 Injected intraperitoneally (i.p.) 15 min before Tyr-K-MIF-1, antagonists of H1 (diphenhydramine, 100 mg kg,1) or H2 (famotidine, 0.3 and 0.6 mg kg,1) histamine receptors diminished peptide antinociceptive effect. Simultaneous H1 - and H2 blockade, as well as pretreatment with 5 mg kg,1 dimaprit (H2 agonist) abolished Tyr-K-MIF-1-induced analgesia. Tyr-K-MIF-1-induced analgesia was also abolished by treatment with R-(,)-methylhistamine (10 mg kg,1, i.p.), an H3 histamine receptor agonist that acts to inhibit histamine release. 4 Our results together with data reported in the literature support the conclusion that activation of the histaminergic system is involved in the mechanism of Tyr-K-MIF-1-induced antinociception. [source]


The role of accounting and the accountant in the environmental management system

BUSINESS STRATEGY AND THE ENVIRONMENT, Issue 3 2001
Trevor D. Wilmshurst
This paper explores the role of accounting and the accountant in the Environmental Management System (EMS). This study was founded on a postal survey of chief executive officers (CEOs) and chief financial officers (CFOs) from the top 500 listed Australian companies. From responses to the surveys, this paper firstly documents the adoption of environmental accounting processes by respondent companies and secondly management attitudes as to the role of environmental accounting in these companies. The senior executives responding to the survey suggest that they believe the environment is an important issue, and recognize the need for a business response. However, there appeared to be limited participation of the accountant in the EMS, which suggests there is a gap between the aggregate observations of this sample and literature support with respect to the role of environmental accounting. It is suggested that this might reflect a lack of understanding of the potential role accounting and the accountant could (and arguably should) play as a member of the EMS team. It is the intention of this paper to provide some input to enhance an understanding of the potential and important role accounting and the accountant could play in the EMS. Copyright © 2001 John Wiley & Sons, Ltd. and ERP Environment [source]


Diffusion of Medical Progress: Early Spinal Immobilization in the Emergency Department

ACADEMIC EMERGENCY MEDICINE, Issue 11 2007
Mark Hauswald MD
Objectives: To examine the spread of new techniques of spinal care through one state's emergency departments (EDs). Methods This was a telephone survey of all 36 EDs in a single state. One physician from each ED was contacted and given a short structured survey instrument to determine when patients who arrived at the ED on backboards were removed from the backboards. Removal was classified as "immediate" if it was done before clinical or radiographic exclusion of cervical spine injury and "delayed" if it was done only after interpretation of any indicated diagnostic radiologic procedures. Further questions were asked to determine if all physicians in the group used the same technique and how this technique had been adopted. Results In all but four hospitals, patients were removed from backboards in the same manner by all physicians, using a protocol or standard procedure. Fifteen of these did immediate and seventeen did delayed removal. In all but one case, the approach of immediate removal was initiated at the hospital by a physician trained or recently working at a university facility. Eight respondents stated that transport service requirements influenced their decision. Conclusions Although logic and the medical literature support removing all patients from a backboard immediately, physicians were unlikely to change their practice after their formal training had been completed until a new member of their group had done so. [source]