Comprehensive Literature (comprehensive + literature)

Distribution by Scientific Domains

Terms modified by Comprehensive Literature

  • comprehensive literature review
  • comprehensive literature search

  • Selected Abstracts


    Systematic review: impact of constipation on quality of life in adults and children

    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 9 2010
    J. BELSEY
    Aliment Pharmacol Ther,31, 938,949 Summary Background, Comparison of quality of life (QoL) across disease areas requires the use of appropriate tools. Although many studies have investigated QoL in constipation, most used disease-specific tools that are inappropriate for cross-comparisons. Aims, To identify studies of QoL in constipation and to compare these results with other chronic conditions. Methods, A comprehensive literature search identified studies in constipation that used a generic QoL tool. Results were statistically pooled where possible and compared with published results using the same tools in other chronic conditions. Results, A total of 13 qualifying studies were identified, 10 in adults and three in children. Results from eight studies using the SF-36/12 tools were pooled; the remaining five were narratively reported. Mental and physical components of QoL scores were consistently impaired in both adult and child populations, with the greatest impact being seen in secondary care studies. Mental health effects predominated over physical domains. The magnitude of impact was comparable with that seen in patients with allergies, musculoskeletal conditions and inflammatory bowel disease. Conclusions, The impact of constipation on QoL is significant and comparable with other common chronic conditions. Improving management may prove to be an effective way of improving QoL for a substantial number of patients. [source]


    Prevalence and time trends in obesity among adult West African populations: a meta-analysis

    OBESITY REVIEWS, Issue 4 2008
    A. R. Abubakari
    Summary The objective of this study was to determine the distribution of and trends in obesity in adult West African populations. Between February and March 2007, a comprehensive literature search was conducted using four electronic databases. Journal hand searches, citations and bibliographic snowballing of relevant articles were also undertaken. To be included, studies had to be population-based, use well-defined criteria for measuring obesity, present data that allowed calculation of the prevalence of obesity and sample adult participants. Studies retrieved were critically appraised. Meta-analysis was performed using the DerSimonian-Laird random effect model. Twenty-eight studies were included. Thirteen studies were conducted in urban settings, 13 in mixed urban/rural and one in rural setting. Mean body mass index ranged from 20.1 to 27.0 kg2. Prevalence of obesity in West Africa was estimated at 10.0% (95% CI, 6.0,15.0). Women were more likely to be obese than men, odds ratios 3.16 (95% CI, 2.51,3.98) and 4.79 (95% CI, 3.30,6.95) in urban and rural areas respectively. Urban residents were more likely to be obese than rural residents, odds ratio 2.70 (95% CI, 1.76,4.15). Time trend analyses indicated that prevalence of obesity in urban West Africa more than doubled (114%) over 15 years, accounted for almost entirely in women. Urban residents and women have particularly high risk of overweight/obesity and obesity is rising fast in women. Policymakers, politicians and health promotion experts must urgently help communities control the spread of obesity in West Africa. [source]


    Development of an educational programme for caregivers of people aging with multiple sclerosis

    OCCUPATIONAL THERAPY INTERNATIONAL, Issue 1 2008
    Marcia Finlayson
    Abstract This article describes a three-phase project to identify and develop an occupational therapy response to the challenges experienced by caregivers of middle-aged and older adults with multiple sclerosis (MS). In Phase 1 302 caregivers of middle-aged and older adults with MS were interviewed by telephone to identify the care-giving challenges they experienced. A total of eight challenges were identified, with the four most prevalent ones including finding and using formal support services, managing the emotional aspects of caregiving, doing the physical aspects of care-giving and dealing with informal supports. In Phase 2 a comprehensive literature review was conducted to identify existing caregiver education programmes that could be used to address these challenges. None of the 21 programmes that were located addressed all of the challenges identified through the Phase 1 interviews. In response, a new five-session psycho-educational group programme entitled ,Meeting the Challenges of MS' was developed in Phase 3. The programme was empirically grounded in Phase 1 findings, and drew on theory to guide group process and sequencing. The findings from Phases 1 and 2 and the resulting programme cannot be generalized to caregivers of younger adults with MS, although the steps taken to develop this programme have the potential for replication with other populations served by occupational therapists. Copyright © 2008 John Wiley & Sons, Ltd. [source]


    Comprehensive review of conventional and non-conventional methods of management of recurrent vulvovaginal candidiasis

    AUSTRALIAN AND NEW ZEALAND JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Issue 4 2007
    Cathy WATSON
    Abstract Recurrent vulvovaginal candidiasis (VVC) is a condition what causes women a great deal of discomfort, inconvenience, and sometimes has psychological sequelae.1 This condition is notoriously difficult to manage. Conventional management is generally favoured by medical practitioners. Some practitioners prefer not to offer other options because of significant possible side-effects and the lack of research supporting alternative treatments. There are many studies and much available information surrounding uncomplicated VVC, including two systematic reviews.2,3 In the area of recurrent VVC however, quality conclusive studies are scarce, and recurrent VVC is featured infrequently in randomised controlled trials (RCTs). Systematic reviews that strongly support a particular pharmacological method of conventional management of recurrent VVC over another are absent from medical literature. Recommendations are largely formed on the basis of scanty RCTs and expert opinion. There is even less conclusive evidence in the area of alternative therapies; yet despite this, anecdotally many practitioners (both alternative and mainstream) continue to advocate certain treatments in the absence of any reliable cure that can be confidently prescribed. As the use of methods other than mainstream medicine becomes more widespread, it is important to be aware of both conventional and non-conventional management of recurrent vulvovaginal candidiasis. Practitioners need to ascertain their patient's preference and treatment history. It is difficult to find comprehensive literature assessing both approaches. Giving women the most up-to-date and relevant information, and different management options, is essential in allowing them to make informed decisions. This review critically assesses both mainstream and less conventional approaches in the management of recurrent VVC. [source]